Immunoexpression of E-cadherin in oral potentially malignant disorders, oral squamous cell carcinoma and its correlation with clinicopathological parameters

The most common malignancy of the head and neck region is “oral squamous cell carcinoma” (OSCC) because its low survival rate increasing incidence in some geographic areas. The process invasion metastasis, which noted cancers, requires loss cell-to-cell attachment. It therefore important to identify a marker that would help identification lesions acquire ability transform into OSCC. Cell-to-cell adhesion motility are monitored by E-cadherin; associated with OSCC progression. Early detection, proper analysis, correct handling oral potentially malignant disorder (OPMD) beneficial preventing Thus, purpose present study expression determine role E-cadherin OPMD OSCC.